PERSONAL EXPERIENCE

   Dr. Liang graduated at Department of Microbiology, College of Life Science, NanKai University and got Ph.D at National Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences. He finished his postdoc at Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Then, he worked as a Research Fellow at Surgical Neurology Branch, NINDS,NIH, for 2 years. In 2007, he was an Assistant professor at Department of Radiology, School of Medicine, Howard University. Dr. Liang currently is a principal invesitigator at Division of Nanobiology and Nanomedicine, National Center for Nanoscience and Technology of China.

RESEARCH INTRODUCTION

   Nanotechnology is to utilize matter smaller than 100 nanometers and takes advantages of properties that are only presented at this nano level. The studies in our laboratory are mainly to explore and elucidate the basic and translational issues in biology and medicine by unique and novel nanotechnology. There are two projects currently ongoing in our group.

    1. Circumvent malignant tumor by innovative nanotechnology
     Malignant tumor is one of the most notorious diseases devastating human lives. Conventional cancer chemotherapeutics utilize natural or synthetic compounds to inhibit cancer cell growth and proliferation, but often accompanying this process is the destruction of healthy cells and tumor becomes incurable due to required multidrug resistance. Nanotechnology will have a revolutionary impact on cancer diagnosis and chemotherapy due to the exceptional characteristics of nanoparticles. Nanomedicine is one of the disciplines that will benefit from this technology the most. It is critical to screen and identify novel nanoparticles with an exclusive anticancer character in vitro and in vivo. The innovative nanoparticles are been developing to efficiently pass through plasma membrane, deliver and release plenty anti-cancer drugs in targeted cells and present less toxicity.This finding may inspire researchers to develop a new generation of nanocompounds with inventive non-traditional approach for cancer treatment. The exclusive nanomedicine will allow for more precise and effective tumor-targeted treatment with less toxicity of cancer chemotherapy.

    2. Improve the AIDS treatment by novel nanotechnique
     Acquired immune deficiency syndrome (AIDS) is one of serious infectious diseases destroying human health. Chinese government announced a series of policies and invested tremendous efforts for comprehensive HIV/AIDS prevention and treatment of AIDS. Production of efficient vaccines for AIDS prevention and novel medicines for AIDS treatment are two strategies for effectively preventing the propagation and expand of HIV. In our laboratory, we are employing the innovative nanotechnique to increase the solubility and improve the bioavailability of anti-AIDS compounds. Ongoing studies increase the probability to get more pre-drug candidates for further pre-clinical trials of AIDS treatment. In