The scientific program will consist of a series of invited plenary lectures, along with presentations of invited and contributing papers in the format of oral and poster sessions. In addition to discussion of the latest experimental results in all areas related to nanobiomedical sciences and nanosafety evaluation, the symposium will focus on the future research directions. The symposium official language is English.
UC-NBM2008 will cover the scientific topics including:
1. Cellular and Molecular Basis of Nanomedicine in Therapeutics and Diagnostics;
2. Toxicological and Nanobiological Effects of Nanomedicines;
3. Nanotechnology, their Clinical Applications and related Human Health as well as Environmental Effects;
4. Nanobiomedical Risk Assessment and Regulatory Issues;
5. Standardization of Nanotechnology and Future Directions.
The 331st Fragrant Hill Science Conference Series
Program
Co-Organized by
Fragrant Hill Science Conference (China)
National Center for Nanosciences and Technology (China)
National Cancer Institute (USA)
National Institute of Environmental Health Sciences (USA)
Supported by
Chinese Academy of Sciences
Ministry of Science and Technology of China (MOST973)
Program
October 20, 2008
10:00-20:00 Registration (at the hall of Fragrant Hill Hotel)
18:00-20:00 Reception (Fragrant Hill Restaurant)
October 21, AM
Session 1: Opening Remark, and Overview of Nanomedicine Programs and Activities in China and U.S. (1)
Chairpersons: The Executive Chairs of the Fragrant Hill Science Conference:
Qide Hanㄛ Xian`en Zhang, Xishan Hao, Zhifang Chai, Yuliang Zhao Robert P. Blumenthal, Michael M.Gottesman, Piotr Grodzinski
8:30-8:40 Introduction of the Fragrant Hill Science Conference (FHSC)
Prof. Bingxin Yang, the director of FHSC office.
8:40-9:00 Welcome and Opening Remarks
Hesheng Chen, Director General, IHEP, CAS
Xian`en Zhang, Director General, MOST
Minghua Liu, Deputy Director General, CAS
Piotr Grodzinski, Ph.D. National Institutes of Health,
Robert Blumenthal, Ph.D. National Institutes of Health,
Yuliang Zhao, Ph.D. The chair of local organization committee,
Introduction of Executive Chairmen of the 331st FHS Conference
9:00-9:30 An Overview of Nanoscience and Nanotechnology Research in China
Chen Wang, Ph.D.
Director General, National Center for Nanoscience and Technology of China
9:30-10:00 An Overview of NIH-Supported Nanoscience and Nanotechnology Research
Nancy E. Miller, Ph.D.
Executive Secretary, Trans-NIH Nanotechnology Task Force
Office of Science Policy Analysis
Office of the Director, NIH
10:00- 10:30 Break (Photograph of all Participants)
10:30-11:00 An Overview of MOST-Supported Nanomedicine and Nanobiotechnology Research
Xian`en Zhang, Ph.D.
General Director, Department of Basic Research
The Ministry of Science and Technology of China
11:00-11:30 Multidrug Resistance in Cancer: A New Challenge for Nanobiology
Michael M. Gottesman, M.D.
Deputy Director for Intramural Research, NIH
11:30-12:10 Discussion
12:10-13:10 Lunch (Fragrant Hill Restaurant)
13:10-14:00 Break
October 21, PM
Session 1: Overview of Nanomedicine Programs and Activities in China and U.S. (2)
Chairpersons: Xian`en Zhang, Michael M. Gottesman
14:00 每 14:30 The Workings of NCI Nanotechnology for Cancer 每 An Opportunity for a New Class of Diagnostic anTherapeuticSolutions Based on Nanotechnology
Piotr Grodzinski, Ph.D.
Director, NCI Alliance for Nanotechnology in Cancer
14:30 每 15:00 Cancer Nano-Chemotherapeutics: Do Not Kill Cells but HighlyInhibit Tumor Growth
Yuliang Zhao, Ph.D.
Director, Nanosafety Lab, and Department of Nanobiology and Nanomedicines,
National Center for Nanoscience and Technology of China, and
Institute of High Energy Physics, Chinese Academy of Sciences
15:00 每 17:30 Fragrant Hill Tour (Festival of red leaf in the Park)
18:00 - 19:00 Dinner (Fragrant Hill Restaurant)
19:00 - 20:30 Brainstorm Panel Discussion
Chairmans Lee Jia, Ning Zhang and Xing-Jie Liang,
〞 To explore similarities and differences in structures and research approaches to nanotechnology between China and USA, brainstorm potentials, and identify collaborations.
Invited Speaker: Lee Jia, Ph.D, Project Manager, Developmental Therapeutics Program, DTCD/NCI,NIH,
〞 Sino-USA Collaboration: Challenges and Opportunities for Advancing Nanomedicine.
Invited Speaker: Ning Zhang, Professor, Ph.D.
Director, CAS-Tianjin Research Center for Cancer Nanotechnology, Tianjin Cancer Hospital and Tianjin Medical University.
〞 A Brief Introduction of The Research Center for Cancer Nanotechnology of China
October 22, AM
Session 2: Molecular Basis of Nanomedicine (Basic and Mechanistic Studies for Use of Nanomaterials in Therapeutics and Diagnostics)
Session Chair: Piotr Grodzinski, Minghua Liu
8:30 每 8:50 Rational Design of Therapeutic Nanovectors
Mauro Ferrari Ph.D.
Professor, Department of Experimental Therapeutics
The University of Texas M. D. Anderson Cancer Center
8:50 每 9:10 Single-Molecule Study of Growth Factor Receptor in Living Cells
Xiaohong Fang, Ph.D
Professor, Institute of Chemistry, Chinese Academy of Sciences
9:10 每 9:30 Nanomechanics and Cell Signaling
Kuan Wang, Ph.D.
Chief, Laboratory of Muscle Biology
National Institute of Arthritis and Musculoskeletal
and Skin Diseases, NIH
9:30 每 9:50 Molecular Designer of Self-assembling Peptide Nanomaterials: Medical Applications
Xiaojun Zhao, Ph.D.
Professor, Medical School, Sichuan University,
9:50 每 10:10 Molecular Classification and Individual Therapy of Gastric and Colorectal Cancer: Current Status andProspect in China
Youyong Lu, M.D. Ph.D
Professor, School of Oncology, Peking University.
10:10 每 10:30 Coffee break
Session 3: The Molecular Basis for Engineered Nanomaterial Interactions with Human Health and the Environment
Session Chair: Zhifang Chai, Sally Tinkle,
10:30 - 10:50 Correlating Structure with Toxicity for Engineered Nanoparticles: Towards Safety by Design
Vickie Colvin, Ph.D.
Professor, Departments of Chemistry and Chemical & Biomolecular Engineering, Rice University
10:50 每 11:10 The Environmental Impacts of Nanotechnology
Gui-Bing Jiang, Ph.D
Vice Director, Research Center for Eco-Environmental Sciences, CAS
11:10 每 11:30 Nanotoxicology as a Predictive Science: Use of a Hierarchical Oxidative Stress Screening Paradigm
Andre Nel, M.B.Ch.B., Ph.D.
Chief, Division of NanoMedicine
University of California, Los Angeles School of Medicine
11:30 每 11:50 Health Impacts of Engineered Nanomaterials
Chunying Chen, Ph.D, M.D.
Professor, National Center for Nanoscience and Technology of China
11:50-12:10 Use of Sentinel Organs to Determine Nanomaterial Penetration of Mouse Skin
Paul Howard, Ph.D.
Director, NTP Center for Phototoxicology, NIEHS.
12:10- 13:10 Lunch (Fragrant Hill Restaurant)
13:10- 14:00 Break
October 22, PM
Session 4: Development of ※Smart§ Nanoparticles for Cancer Therapy and Imaging (1)
Session Chair: Vickie Colvin, Yuliang Zhao
14:00- 14:20 Multifunctional Nanoparticles for Molecular Imaging and Targeted Therapy of Cancer
Shuming Nie, Ph.D.
Chair and Professor, Departments of Biomedical Engineering and Chemistry, Emory University/Georgia Institute of Technology
14:20- 14:40 Fluorescent Semiconductor Quantum Dot-Based Nanobioprobes
Daiwen Pang, Ph.D
Professor, Wuhan University
14:40-15:00 Understanding Principals of Nanomaterial Biocompatibility Using Integrated ※Omics Approaches§
Brian Thrall, Ph.D.
Cell Biology and Biochemistry Group, Biological Sciences DivisionPacific Northwest National Laboratory
15:00-15:20 Using Micro-Nano-Technology to Construct an In-Vitro Model for Living Tissues
Xingyu Jiang, Ph.D
Professor, National Center for Nanoscience and Technology of China
15:20-15:40 Break
Session 4: Development of ※Smart§ Nanoparticles for Cancer Therapy and Imaging (2)
15:40-16:00 Can Inert Iron Oxide Nanoparticle Function as Enzyme?
Xiyun Yan, Ph.D.
Institute of Biophysics, Chinese Academy of Sciences
16:00-16:20 Engineered Drug Therapies Using Fabrication Methods from the Microelectronics Industry
Joseph M. DeSimone, Ph.D.
Professor, Departments of Chemistry and Chemical Engineering,
University of North Carolina at Chapel Hill /and North Carolina State University
16:20-16:40 Nanomedicine Opportunities with ※Theranostic§ PFC Nanoparticles
Greg Lanza, M.D., Ph.D.
Assistant Professor, Medicine and Biomedical Engineering
Washington University in St. Louis,
16:40-17:00 Carbon Nanomaterials Towards Cancer Therapy & Imaging
Hongfang Sun, Ph.D
Peking University
17:00-17:30 Group discussion
17:30-21:30 Banquet at Beijing Roast Duck Restaurant, and A night tour (by bus) to Olympic Game Village
Banquet is hosted by Prof. Jiayang Li, Vice President of Chinese Academy of Sciences
October 23, AM
Session 5: Biomarker and Targeted Delivery (1)
Session Chair: Andre Nel, Xiaohong Fang
8:30-8:50 Systems Biology Driven In Vitro Diagnostic and Measurement Technologies or Cancer
James R. Heath, Ph.D.
Professor, Department of Chemistry, California Institute of Technology, USA
8:50-9:10 Effective Therapy of Cancer: Therapeutic Nanoparticles
Jie Ma, MD
Professor, Cancer Institute & Hospital,
Chinese Academy of Medical Sciences
9:10-9:30 Multifunctional Nanoparticles for Cancer Diagnosis and Therapy
Miqin Zhang, Ph.D.
Professor, Materials Science & Engineering
University of Washington, USA
9:30-9:50 Preclinical Characterization of Nanoparticles Intended for Cancer Applications
Scott McNeil, Ph.D.
Director, Nanotechnology Characterization Laboratory, SAIC, NCI
9:50-10:10 Anti-tumor Nano Drug Delivery Systems Targeted to Integrins over expressed in Neovasculature and Tumor Cells
Qiang Zhang, Ph.D,
Professor, School of Pharmacology Science, Peking University
10:10 每 10:30 Coffee break
Session 5: Biomarker and Targeted Delivery (2)
Session Chair: Kuan Wang, Scott McNeil,
10:30 - 10:50 Circumvent Tumor Resistance to Chemotherapy improved with Nanobiotechnology
Xing-Jie Liang, Ph.D.
Professor, National Center for Nanoscience and Technology of China
10:50 每 11:10 Targeted Delivery of Hollow Gold Nanospheres for Optoacoustic Imaging and Photothermal Ablation Therapy
Chun Li, Ph.D.
Professor, Department of Experimental Diagnostic Imaging
M. D. Anderson Cancer Center, The University of Texas,
11:10 每 11:30 Iron Oxide Nanoparticle As Contrast Agent for Magnetic Resonance Imaging---Toward Differential Diagnosis and Stem Cell Tracking
Hao Lei, Ph.D.
Professor, Wuhan Institute of Physics and Mathematics,
Chinese Academy of Sciences
11:30 每 11:50 Omid Farokhzad, M.D.
Professor, Laboratory of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women＊s Hospital,
Harvard Medical School,
11:50- 13:00 Lunch (Fragrant Hill Restaurant)
13:00- 14:00 Break
October 23, PM
Session 6: Nanotechnology - Path to the Clinic: Promises and Hurdles
Session Chair: Mauro Ferrari, Omid Farokhzad,
14:00-14:20 Lipid-Based Nanoparticles for Sustained, Targeted and Triggered Delivery of Therapeutics for Cancer Treatment
Robert P. Blumenthal, Ph.D.
Director, Center for Cancer Research Nanobiology Program,
National Cancer Institute, NIH
14:20-14:40 Receptor-Targeted Therapies for Cancer, Inflammation, and Autoimmune Diseases: Applications of Nanotechnology
Philip Low, Ph.D.
Ralph C. Corley Distinguished Professor,
Department of Chemistry, Purdue University
14:40-15:00 Autophagy Induction By Nano C60: Exploring Potential Biomedical Applications
Longping Wen, Ph.D
Professor, University of Science and Technology of China
15:00-15:20 Carbon Nanotubes and Anti-tumor Immunotherapy
Xianda Yang, M.D., Ph.D.
Professor, The Institute of Basic Medical Sciences,
Chinese Academy of Medical Sciences,
15:20-15:40 Polymer Micelles: From Bench to the Bedside
Alexander (Sasha) Kabanov, Ph.D., Dr.Sc.
Professor, University of Nebraska Medical Center
15:40-16:00 Coffee break
16:00-18:00 Summary and Discussion:
Meeting Wrap-Up and Next Steps
Chairpersons: The Executive Chairs of the Conference:
Xian`en Zhang, Xishan Hao, Zhifang Chai, Yuliang Zhao
Robert P. Blumenthal, Michael M. Gottesman, Piotr Grodzinski
18:00 Close Conference
